Medications and Drugs

Medications and Drugs


DRUG CLASS AND MECHANISM: FluMist is a nasal vaccine that protects against infection with the influenza virus or the "flu." FluMist contains live influenza virus that has been weakened so that it causes minimal or no symptoms. When FluMist is inhaled, the body responds to the weakened viruses in FluMist by developing antibodies that fight influenza viruses. These antibodies protect against later infections by the naturally-occurring influenza virus. FluMist is effective only against the strains of influenza virus that are included in it, and the strains of virus change from year to year. FluMist has no effect on the flu once infection has begun. FluMist should be given shortly before the flu season begins to allow time for antibodies to be produced and for protection throughout the entire flu season. FluMist does not prevent 2009 H1N1 (swine flu) virus infection. The FDA approved FluMist in June 2003.

PRESCRIPTION: Yes.

GENERIC AVAILABLE: No.

PREPARATIONS: Intranasal Spray: prefilled single use intranasal spray, 0.2 ml

STORAGE: FluMist should be stored refrigerated between 2-8 C (35-46 F).

PRESCRIBED FOR: FluMist is used for preventing influenza virus infections (flu) in individuals 2 to 49 years of age.

DOSING: Children 2 to 8 years of age who have not previously received. FluMist should be given 2 doses of 0.2 ml one month apart. Children 2 to 8 years of age, who previously received FluMist and adults 9 to 49 years of age, should be given 1 dose (0.2 ml) each season. FluMist is administered by inhaling through the nose and is not given by injection. Half of a single dose (0.1 ml) should be inhaled into each nostril while in a standing position.

Since FluMist contains viruses that are likely to cause the flu in the upcoming season, FluMist developed for previous seasons will not be effective and should not be used.

DRUG INTERACTIONS: Children 5 to 17 years of age who are receiving aspirin therapy should not be given FluMist because of the association between aspirin, influenza infection and Reye's syndrome.

Use of FluMist together with antiviral drugs that are active against the influenza virus has not been evaluated. Since there is a potential for these agents to reduce the effectiveness of FluMist (by preventing infection with the weakened viruses in FluMist), such antiviral agents should not be administered until 2 weeks after FluMist therapy, and FluMist should not be administered until 48 hours after antiviral therapy is discontinued.

PREGNANCY: FluMist should not be given to pregnant women.

NURSING MOTHERS: Use of FluMist during breast feeding has not been adequately evaluated, and it is not known whether FluMist is excreted in breast milk.

SIDE EFFECTS: The most common side effects of FluMist are cough, runny nose, nasal congestion, sore throat, headache, restlessness, muscle aches, tiredness or weakness and fever. Hypersensitivity reactions have also been reported. FluMist should not be administered to individuals with asthma because it may increase wheezing.

Reference: FluMist Prescribing Information, 2009

Last Editorial Review: 11/23/2009

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Important Safety Information

Vimpat (lacosamide) is a medicine that is used with other medicines to treat partial onset seizures in patients 17 years of age and older with epilepsy. Vimpat is generally well-tolerated, but may not be for everyone. Ask your doctor if Vimpat is right for you. Antiepileptic drugs, including Vimpat, may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call your healthcare provider right away if you have new or worsening symptoms of depression, any unusual changes in mood or behavior, or suicidal thoughts, behavior, or thoughts about self harm that you have never had before or may be worse than before. Please see additional patient information in the Medication Guide at the end of the full prescribing information. This information does not take the place of talking with your healthcare provider about your condition or your treatment. Please see additional Patient Safety Information
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What is swine flu (novel H1N1 influenza A swine flu)?

Swine flu (swine influenza) is a respiratory disease caused by viruses (influenza viruses) that infect the respiratory tract of pigs and result in nasal secretions, a barking-like cough, decreased appetite, and listless behavior. Swine flu produces most of the same symptoms in pigs as human flu produces in people. Swine flu can last about one to two weeks in pigs that survive. Swine influenza virus was first isolated from pigs in 1930 in the U.S. and has been recognized by pork producers and veterinarians to cause infections in pigs worldwide. In a number of instances, people have developed the swine flu infection when they are closely associated with pigs (for example, farmers, pork processors), and likewise, pig populations have occasionally been infected with the human flu infection. In most instances, the cross-species infections (swine virus to man; human flu virus to pigs) have remained in local areas and ha...

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